Human INSIG2 activation kit by CRISPRa

CAT#: GA109600

INSIG2 CRISPRa kit - CRISPR gene activation of human insulin induced gene 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: INSIG2
• Locus ID: 51141
• Kit Components:

  GA109600G1, INSIG2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109600G2, INSIG2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109600G3, INSIG2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_016133, NM_001321329, NM_001321330, NM_001321331, NM_001321332, NM_001321333
• Synonyms: MGC26273
• Summary: The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi. [provided by RefSeq, Jul 2008]