Human Cytoplasmic dynein 1 light intermediate chain 1 (DYNC1LI1) activation kit by CRISPRa

CAT#: GA109602

DYNC1LI1 CRISPRa kit - CRISPR gene activation of human dynein cytoplasmic 1 light intermediate chain 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DYNC1LI1
• Locus ID: 51143
• Kit Components:

  GA109602G1, DYNC1LI1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109602G2, DYNC1LI1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109602G3, DYNC1LI1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001329135, NM_016141
• Synonyms: DLC-A; DNCLI1; LIC1
• Summary: The protein encoded by this gene belongs to light intermediate subunit family, whose members are components of the multiprotein cytoplasmic dynein complex, which is involved in intracellular trafficking and chromosome segregation during mitosis. The protein plays a role in moving the spindle assembly checkpoint (SAC) from kinetochores to spindle poles. The protein may also mediate binding to other cargo molecules to facilitate intracellular vesicle trafficking. [provided by RefSeq, Jul 2016]