Human SS18L2 activation kit by CRISPRa

CAT#: GA109636

SS18L2 CRISPRa kit - CRISPR gene activation of human SS18 like 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SS18L2
• Locus ID: 51188
• Kit Components:

  GA109636G1, SS18L2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109636G2, SS18L2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109636G3, SS18L2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_016305, NM_001370300
• Synonyms: KIAA-iso
• Summary: Synovial sarcomas occur most frequently in the extremities around large joints. More than 90% of cases have a recurrent and specific chromosomal translocation, t(X;18)(p11.2;q11.2), in which the 5-prime end of the SS18 gene (MIM 600192) is fused in-frame to the 3-prime end of the SSX1 (MIM 312820), SSX2 (MIM 300192), or SSX4 (MIM 300326) gene. The SS18L2 gene is homologous to SS18. [supplied by OMIM, Jul 2002]