Human CPA4 activation kit by CRISPRa

CAT#: GA109644

CPA4 CRISPRa kit - CRISPR gene activation of human carboxypeptidase A4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CPA4
• Locus ID: 51200
• Kit Components:

  GA109644G1, CPA4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109644G2, CPA4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109644G3, CPA4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001163446, NM_016352
• Synonyms: CPA3
• Summary: This gene is a member of the carboxypeptidase A/B subfamily, and it is located in a cluster with three other family members on chromosome 7. Carboxypeptidases are zinc-containing exopeptidases that catalyze the release of carboxy-terminal amino acids, and are synthesized as zymogens that are activated by proteolytic cleavage. This gene could be involved in the histone hyperacetylation pathway. It is imprinted and may be a strong candidate gene for prostate cancer aggressiveness. [provided by RefSeq, Jul 2008]