Human ABI3 activation kit by CRISPRa

CAT#: GA109658

ABI3 CRISPRa kit - CRISPR gene activation of human ABI family member 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ABI3
• Locus ID: 51225
• Kit Components:

  GA109658G1, ABI3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109658G2, ABI3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109658G3, ABI3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001135186, NM_016428
• Synonyms: NESH; SSH3BP3
• Summary: This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]