Human TBC1D7 activation kit by CRISPRa

CAT#: GA109681

TBC1D7 CRISPRa kit - CRISPR gene activation of human TBC1 domain family member 7

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TBC1D7
• Locus ID: 51256
• Kit Components:

  GA109681G1, TBC1D7 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109681G2, TBC1D7 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109681G3, TBC1D7 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001143964, NM_001143965, NM_001143966, NM_001258457, NM_001318805, NM_001318806, NM_016495
• Synonyms: MGCPH; PIG51; TBC7
• Summary: This gene encodes a member of the TBC-domain containing protein family. The encoded protein functions as a subunit of the tuberous sclerosis TSC1-TSC2 complex which plays a role in the regulation of cellular growth and differentiation. Mutations in this gene have been associated with autosomal recessive megalencephaly. Alternative splicing results in multiple transcript variants. Naturally occurring readthrough transcription occurs between this locus and downstream LOC100130357. [provided by RefSeq, Jan 2016]