Human GMPR2 activation kit by CRISPRa

CAT#: GA109711

GMPR2 CRISPRa kit - CRISPR gene activation of human guanosine monophosphate reductase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GMPR2
• Locus ID: 51292
• Kit Components:

  GA109711G1, GMPR2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109711G2, GMPR2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109711G3, GMPR2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001002000, NM_001002001, NM_001002002, NM_001283021, NM_001283022, NM_001283023, NM_016576, NR_104265, NM_001351022, NM_001351023, NM_001351024, NM_001351025, NM_001351026
• Synonyms: GMPR 2
• Summary: This gene encodes an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of guanosine monophosphate (GMP) to inosine monophosphate (IMP). The protein also functions in the re-utilization of free intracellular bases and purine nucleosides. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2017]