Human CYP39A1 activation kit by CRISPRa

CAT#: GA109721

CYP39A1 CRISPRa kit - CRISPR gene activation of human cytochrome P450 family 39 subfamily A member 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CYP39A1
• Locus ID: 51302
• Kit Components:

  GA109721G1, CYP39A1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109721G2, CYP39A1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109721G3, CYP39A1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001278738, NM_001278739, NM_016593
• Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]