Human KCNK9 activation kit by CRISPRa

CAT#: GA109724

KCNK9 CRISPRa kit - CRISPR gene activation of human potassium two pore domain channel subfamily K member 9

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KCNK9
• Locus ID: 51305
• Kit Components:

  GA109724G1, KCNK9 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109724G2, KCNK9 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109724G3, KCNK9 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001282534, NM_016601, NR_104210
• Synonyms: K2p9.1; KT3.2; TASK-3; TASK3
• Summary: This gene encodes a protein that contains multiple transmembrane regions and two pore-forming P domains and functions as a pH-dependent potassium channel. Amplification and overexpression of this gene have been observed in several types of human carcinomas. This gene is imprinted in the brain, with preferential expression from the maternal allele. A mutation in this gene was associated with Birk-Barel dysmorphism syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2017]