Human TXNDC3 (NME8) activation kit by CRISPRa

CAT#: GA109733

NME8 CRISPRa kit - CRISPR gene activation of human NME/NM23 family member 8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NME8
• Locus ID: 51314
• Kit Components:

  GA109733G1, NME8 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109733G2, NME8 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109733G3, NME8 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_016616
• Synonyms: CILD6; HEL-S-99; NM23-H8; sptrx-2; SPTRX2; TXNDC3
• Summary: This gene encodes a protein with an N-terminal thioredoxin domain and three C-terminal nucleoside diphosphate kinase (NDK) domains, but the NDK domains are thought to be catalytically inactive. The sea urchin ortholog of this gene encodes a component of sperm outer dynein arms, and the protein is implicated in ciliary function. Mutations in this gene are implicated in primary ciliary dyskinesia type 6. [provided by RefSeq, Nov 2009]