Human Archaemetzincin 2 (AMZ2) activation kit by CRISPRa

CAT#: GA109740

AMZ2 CRISPRa kit - CRISPR gene activation of human archaelysin family metallopeptidase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AMZ2
• Locus ID: 51321
• Kit Components:

  GA109740G1, AMZ2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109740G2, AMZ2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109740G3, AMZ2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001033569, NM_001033570, NM_001033571, NM_001033572, NM_001033574, NM_001289054, NM_001289056, NM_016627, NM_001346471, NM_001346472, NM_001346473, NM_001346474, NM_001346475, NM_001346476, NM_001346477, NM_001346478, NM_001346479, NM_001346480, NM_001346481, NM_001346482, NM_001346483, NM_001346484, NM_001346485, NR_144442, NR_144443
• Synonyms: archaelysin family metallopeptidase 2; archaemetzincin-2; archaemetzincins-2
• Summary: The protein encoded by this gene is a zinc metalloprotease that displays some activity against angiotensin-3. The encoded protein is inhibited by the aminopeptidase inhibitor amastatin, as well as by the general inhibitors o-phenanthroline and batimastat. Defects in this gene may be associated with lung tumorigenesis. [provided by RefSeq, Oct 2016]