Human CHST15 activation kit by CRISPRa

CAT#: GA109764

CHST15 CRISPRa kit - CRISPR gene activation of human carbohydrate sulfotransferase 15

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CHST15
• Locus ID: 51363
• Kit Components:

  GA109764G1, CHST15 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109764G2, CHST15 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109764G3, CHST15 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001270764, NM_001270765, NM_014863, NM_015892
• Synonyms: BRAG; GALNAC4S-6ST
• Summary: Chondroitin sulfate (CS) is a glycosaminoglycan which is an important structural component of the extracellular matrix and which links to proteins to form proteoglycans. Chondroitin sulfate E (CS-E) is an isomer of chondroitin sulfate in which the C-4 and C-6 hydroxyl groups are sulfated. This gene encodes a type II transmembrane glycoprotein that acts as a sulfotransferase to transfer sulfate to the C-6 hydroxal group of chondroitin sulfate. This gene has also been identified as being co-expressed with RAG1 in B-cells and as potentially acting as a B-cell surface signaling receptor. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012]