Human CRLF3 activation kit by CRISPRa

CAT#: GA109777

CRLF3 CRISPRa kit - CRISPR gene activation of human cytokine receptor like factor 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CRLF3
• Locus ID: 51379
• Kit Components:

  GA109777G1, CRLF3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109777G2, CRLF3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109777G3, CRLF3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_015986, NR_073118
• Synonyms: CREME-9; CREME9; CRLM9; CYTOR4; FRWS; p48.2
• Summary: This gene encodes a cytokine receptor-like factor that may negatively regulate cell cycle progression at the G0/G1 phase. Studies of the related rat protein suggest that it may regulate neuronal morphology and synaptic vesicle biogenesis. This gene is one of several genes located in the neurofibromatosis type I tumor suppressor region on the q arm of chromosome 17, a region that is subject to microdeletions, duplications, chromosomal breaks and rearrangements. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2 and 5. [provided by RefSeq, Aug 2012]