Human WNT16 activation kit by CRISPRa

CAT#: GA109780

WNT16 CRISPRa kit - CRISPR gene activation of human Wnt family member 16

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: WNT16
• Locus ID: 51384
• Kit Components:

  GA109780G1, WNT16 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109780G2, WNT16 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109780G3, WNT16 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_016087, NM_057168
• Synonyms: wingless-related MMTV integration site 16; wingless-type MMTV integration site family, member 16
• Summary: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It contains two transcript variants diverging at the 5' termini. These two variants are proposed to be the products of separate promoters and not to be splice variants from a single promoter. They are differentially expressed in normal tissues, one of which (variant 2) is expressed at significant levels only in the pancreas, whereas another one (variant 1) is expressed more ubiquitously with highest levels in adult kidney, placenta, brain, heart, and spleen. [provided by RefSeq, Jul 2008]