Human PPME1 activation kit by CRISPRa

CAT#: GA109790

PPME1 CRISPRa kit - CRISPR gene activation of human protein phosphatase methylesterase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PPME1
• Locus ID: 51400
• Kit Components:

  GA109790G1, PPME1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109790G2, PPME1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109790G3, PPME1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001271593, NM_016147
• Synonyms: PME-1
• Summary: This gene encodes a protein phosphatase methylesterase localized to the nucleus. The encoded protein acts on the protein phosphatase-2A catalytic subunit and supports the ERK pathway through dephosphorylation of regulatory proteins. It plays a role in malignant glioma progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]