Human LCMT1 activation kit by CRISPRa

CAT#: GA109814

LCMT1 CRISPRa kit - CRISPR gene activation of human leucine carboxyl methyltransferase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: LCMT1
• Locus ID: 51451
• Kit Components:

  GA109814G1, LCMT1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109814G2, LCMT1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109814G3, LCMT1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001032391, NM_016015, NM_016309
• Synonyms: CGI-68; LCMT; PPMT1
• Summary: LCMT1 catalyzes the methylation of the carboxyl group of the C-terminal leucine residue (leu309) of the catalytic subunit of protein phosphatase-2A (PPP2CA; MIM 176915) (De Baere et al., 1999 [PubMed 10600115]). [supplied by OMIM, Mar 2008]