Human REV1 activation kit by CRISPRa

CAT#: GA109816

REV1 CRISPRa kit - CRISPR gene activation of human REV1 DNA directed polymerase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: REV1
• Locus ID: 51455
• Kit Components:

  GA109816G1, REV1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109816G2, REV1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109816G3, REV1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001037872, NM_001321454, NM_001321455, NM_001321458, NM_001321459, NM_001321460, NM_016316, NR_135649, NR_135650, NR_135651, NR_135652, NR_135653
• Synonyms: AIBP80; REV1L
• Summary: This gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein-protein interactions. A suggested role for the human Rev1-like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA. [provided by RefSeq, Mar 2016]