Human GTSE1 activation kit by CRISPRa

CAT#: GA109844

GTSE1 CRISPRa kit - CRISPR gene activation of human G2 and S-phase expressed 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GTSE1
• Locus ID: 51512
• Kit Components:

  GA109844G1, GTSE1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109844G2, GTSE1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109844G3, GTSE1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_016426
• Synonyms: B99
• Summary: The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis. [provided by RefSeq, Jul 2008]