Human Leucyl tRNA synthetase (LARS) activation kit by CRISPRa
CAT#: GA109848
LARS CRISPRa kit - CRISPR gene activation of human leucyl-tRNA synthetase
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | LARS |
Locus ID | 51520 |
Kit Components | GA109848G1, LARS gRNA vector 1 in pCas-Guide-CRISPRa GA109848G2, LARS gRNA vector 2 in pCas-Guide-CRISPRa GA109848G3, LARS gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001317964, NM_001317965, NM_016460, NM_020117 |
Synonyms | hr025Cl; HSPC192; ILFS1; LARS1; LEURS; LEUS; LFIS; LRS; PIG44; RNTLS |
Summary | This gene encodes a cytosolic leucine-tRNA synthetase, a member of the class I aminoacyl-tRNA synthetase family. The encoded enzyme catalyzes the ATP-dependent ligation of L-leucine to tRNA(Leu). It is found in the cytoplasm as part of a multisynthetase complex and interacts with the arginine tRNA synthetase through its C-terminal domain. A mutation in this gene was found in affected individuals with infantile liver failure syndrome 1. Alternatively spliced transcript variants of this gene have been observed. [provided by RefSeq, Dec 2015] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN421682 | LARS - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
{0} Product Review(s)
Be the first one to submit a review