Human TMEM138 activation kit by CRISPRa

CAT#: GA109851

TMEM138 CRISPRa kit - CRISPR gene activation of human transmembrane protein 138

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TMEM138
• Locus ID: 51524
• Kit Components:

  GA109851G1, TMEM138 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109851G2, TMEM138 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109851G3, TMEM138 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001330281, NM_016464, NR_028473
• Synonyms: HSPC196
• Summary: This gene encodes a multi-pass transmembrane protein. Reduced expression of this gene in mouse fibroblasts causes short cilia and failure of ciliogenesis. Expression of this gene is tightly coordinated with expression of the neighboring gene TMEM216. Mutations in this gene are associated with the autosomal recessive neurodevelopmental disorder Joubert Syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]