Human RAB14 activation kit by CRISPRa

CAT#: GA109869

RAB14 CRISPRa kit - CRISPR gene activation of human RAB14, member RAS oncogene family

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RAB14
• Locus ID: 51552
• Kit Components:

  GA109869G1, RAB14 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109869G2, RAB14 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109869G3, RAB14 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_016322
• Synonyms: FBP; RAB-14
• Summary: RAB14 belongs to the large RAB family of low molecular mass GTPases that are involved in intracellular membrane trafficking. These proteins act as molecular switches that flip between an inactive GDP-bound state and an active GTP-bound state in which they recruit downstream effector proteins onto membranes (Junutula et al., 2004 [PubMed 15004230]). [supplied by OMIM, Mar 2009]