Human UFM1 activation kit by CRISPRa

CAT#: GA109880

UFM1 CRISPRa kit - CRISPR gene activation of human ubiquitin fold modifier 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: UFM1
• Locus ID: 51569
• Kit Components:

  GA109880G1, UFM1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109880G2, UFM1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109880G3, UFM1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001286703, NM_001286704, NM_001286705, NM_001286706, NM_016617, NR_104584, NR_104585
• Synonyms: BM-002; C13orf20
• Summary: UFM1 is a ubiquitin-like protein that is conjugated to target proteins by E1-like activating enzyme UBA5 (UBE1DC1; MIM 610552) and E2-like conjugating enzyme UFC1 (MIM 610554) in a manner analogous to ubiquitylation (see UBE2M; MIM 603173) (Komatsu et al., 2004 [PubMed 15071506]). [supplied by OMIM, Dec 2008]