Human BRP44L (MPC1) activation kit by CRISPRa

CAT#: GA109929

MPC1 CRISPRa kit - CRISPR gene activation of human mitochondrial pyruvate carrier 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MPC1
• Locus ID: 51660
• Kit Components:

  GA109929G1, MPC1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109929G2, MPC1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109929G3, MPC1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001270879, NM_016098, NR_073093
• Synonyms: BRP44L; CGI-129; dJ68L15.3; MPYCD
• Summary: The protein encoded by this gene is part of an MPC1/MPC2 heterodimer that is responsible for transporting pyruvate into mitochondria. The encoded protein is found in the inner mitochondrial membrane. Defects in this gene are a cause of mitochondrial pyruvate carrier deficiency. Several transcript variants, some protein coding and one non-protein coding, have been found for this gene. [provided by RefSeq, Aug 2012]