Human RAB23 activation kit by CRISPRa

CAT#: GA109957

RAB23 CRISPRa kit - CRISPR gene activation of human RAB23, member RAS oncogene family

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RAB23
• Locus ID: 51715
• Kit Components:

  GA109957G1, RAB23 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109957G2, RAB23 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109957G3, RAB23 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001278666, NM_001278667, NM_001278668, NM_016277, NM_183227, NR_103822
• Synonyms: HSPC137
• Summary: This gene encodes a small GTPase of the Ras superfamily. Rab proteins are involved in the regulation of diverse cellular functions associated with intracellular membrane trafficking, including autophagy and immune response to bacterial infection. The encoded protein may play a role in central nervous system development by antagonizing sonic hedgehog signaling. Disruption of this gene has been implicated in Carpenter syndrome as well as cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]