Human WBP11 activation kit by CRISPRa

CAT#: GA109964

WBP11 CRISPRa kit - CRISPR gene activation of human WW domain binding protein 11

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: WBP11
• Locus ID: 51729
• Kit Components:

  GA109964G1, WBP11 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109964G2, WBP11 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109964G3, WBP11 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_016312
• Synonyms: NPWBP; PPP1R165; SIPP1; WBP-11
• Summary: This gene encodes a nuclear protein, which colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks. This protein has 95% amino acid sequence identity to the mouse Wbp11 protein. It contains two proline-rich regions that bind to the WW domain of Npw38, a nuclear protein, and thus this protein is also called Npw38-binding protein NpwBP. The Npw38-NpwBP complex may function as a component of an mRNA factory in the nucleus. [provided by RefSeq, Jul 2008]