Human SKIP (INPP5K) activation kit by CRISPRa

CAT#: GA109982

INPP5K CRISPRa kit - CRISPR gene activation of human inositol polyphosphate-5-phosphatase K

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: INPP5K
• Locus ID: 51763
• Kit Components:

  GA109982G1, INPP5K gRNA vector 1 in pCas-Guide-CRISPRa

  GA109982G2, INPP5K gRNA vector 2 in pCas-Guide-CRISPRa

  GA109982G3, INPP5K gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001135642, NM_016532, NM_130766
• Synonyms: PPS; SKIP
• Summary: This gene encodes a protein with 5-phosphatase activity toward polyphosphate inositol. The protein localizes to the cytosol in regions lacking actin stress fibers. It is thought that this protein may negatively regulate the actin cytoskeleton. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]