Human CALML5 activation kit by CRISPRa

CAT#: GA109993

CALML5 CRISPRa kit - CRISPR gene activation of human calmodulin like 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CALML5
• Locus ID: 51806
• Kit Components:

  GA109993G1, CALML5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109993G2, CALML5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109993G3, CALML5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_017422
• Synonyms: CLSP
• Summary: This gene encodes a novel calcium binding protein expressed in the epidermis and related to the calmodulin family of calcium binding proteins. Functional studies with recombinant protein demonstrate it does bind calcium and undergoes a conformational change when it does so. Abundant expression is detected only in reconstructed epidermis and is restricted to differentiating keratinocytes. In addition, it can associate with transglutaminase 3, shown to be a key enzyme in the terminal differentiation of keratinocytes. [provided by RefSeq, Jul 2008]