Human IL17D activation kit by CRISPRa

CAT#: GA110002

IL17D CRISPRa kit - CRISPR gene activation of human interleukin 17D

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IL17D
• Locus ID: 53342
• Kit Components:

  GA110002G1, IL17D gRNA vector 1 in pCas-Guide-CRISPRa

  GA110002G2, IL17D gRNA vector 2 in pCas-Guide-CRISPRa

  GA110002G3, IL17D gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_138284
• Synonyms: IL-17D
• Summary: The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent. [provided by RefSeq, Jul 2008]