Human TPCN1 activation kit by CRISPRa

CAT#: GA110013

TPCN1 CRISPRa kit - CRISPR gene activation of human two pore segment channel 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TPCN1
• Locus ID: 53373
• Kit Components:

  GA110013G1, TPCN1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110013G2, TPCN1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110013G3, TPCN1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001143819, NM_001301214, NM_017901, NM_001351346, NM_001351347
• Synonyms: TPC1
• Summary: Voltage-gated Ca(2+) and Na+ channels have 4 homologous domains, each containing 6 transmembrane segments, S1 to S6. TPCN1 is similar to these channels, but it has only 2 domains containing S1 to S6 (Ishibashi et al., 2000 [PubMed 10753632]). [supplied by OMIM, Mar 2008]