Human PCBP3 activation kit by CRISPRa

CAT#: GA110052

PCBP3 CRISPRa kit - CRISPR gene activation of human poly(rC) binding protein 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PCBP3
• Locus ID: 54039
• Kit Components:

  GA110052G1, PCBP3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110052G2, PCBP3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110052G3, PCBP3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001130141, NM_020528, NM_001348238, NM_001348239, NM_001348240, NM_001348241, NM_001348242, NM_001348243, NM_001348244, NM_001348245, NR_145492, NR_145493
• Synonyms: ALPHA-CP3
• Summary: This gene encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. The protein encoded by this gene lacks the nuclear localization signals found in other subfamily members. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2017]