Human SOX18 activation kit by CRISPRa

CAT#: GA110084

SOX18 CRISPRa kit - CRISPR gene activation of human SRY-box transcription factor 18

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SOX18
• Locus ID: 54345
• Kit Components:

  GA110084G1, SOX18 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110084G2, SOX18 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110084G3, SOX18 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_018419
• Synonyms: HLTRS; HLTS
• Summary: This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein plays a role in hair, blood vessel, and lymphatic vessel development. Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia. [provided by RefSeq, Jul 2008]