Human Anillin (ANLN) activation kit by CRISPRa

CAT#: GA110104

ANLN CRISPRa kit - CRISPR gene activation of human anillin actin binding protein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ANLN
• Locus ID: 54443
• Kit Components:

  GA110104G1, ANLN gRNA vector 1 in pCas-Guide-CRISPRa

  GA110104G2, ANLN gRNA vector 2 in pCas-Guide-CRISPRa

  GA110104G3, ANLN gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001284301, NM_001284302, NM_018685
• Synonyms: FSGS8; scra; Scraps
• Summary: This gene encodes an actin-binding protein that plays a role in cell growth and migration, and in cytokinesis. The encoded protein is thought to regulate actin cytoskeletal dynamics in podocytes, components of the glomerulus. Mutations in this gene are associated with focal segmental glomerulosclerosis 8. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]