Human TOLLIP activation kit by CRISPRa

CAT#: GA110123

TOLLIP CRISPRa kit - CRISPR gene activation of human toll interacting protein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TOLLIP
• Locus ID: 54472
• Kit Components:

  GA110123G1, TOLLIP gRNA vector 1 in pCas-Guide-CRISPRa

  GA110123G2, TOLLIP gRNA vector 2 in pCas-Guide-CRISPRa

  GA110123G3, TOLLIP gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001318512, NM_001318514, NM_001318515, NM_001318516, NM_019009
• Synonyms: IL-1RAcPIP
• Summary: This gene encodes a ubiquitin-binding protein that interacts with several Toll-like receptor (TLR) signaling cascade components. The encoded protein regulates inflammatory signaling and is involved in interleukin-1 receptor trafficking and in the turnover of IL1R-associated kinase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]