Human UGT2B28 activation kit by CRISPRa

CAT#: GA110132

UGT2B28 CRISPRa kit - CRISPR gene activation of human UDP glucuronosyltransferase family 2 member B28

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: UGT2B28
• Locus ID: 54490
• Kit Components:

  GA110132G1, UGT2B28 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110132G2, UGT2B28 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110132G3, UGT2B28 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001207004, NM_053039
• Summary: This gene encodes a member of the uridine diphosphoglucuronosyltransferase protein family. The encoded enzyme catalyzes the transfer of glucuronic acid from uridine diphosphoglucuronic acid to a diverse array of substrates including steroid hormones and lipid-soluble drugs. This process, known as glucuronidation, is an intermediate step in the metabolism of steroids. Two transcript variants encoding different isoforms have been found for this gene. While both isoforms are targeted to the endoplasmic reticulum, only the longer isoform appears to be active. [provided by RefSeq, May 2011]