Human PRMT7 activation kit by CRISPRa

CAT#: GA110137

PRMT7 CRISPRa kit - CRISPR gene activation of human protein arginine methyltransferase 7

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PRMT7
• Locus ID: 54496
• Kit Components:

  GA110137G1, PRMT7 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110137G2, PRMT7 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110137G3, PRMT7 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001184824, NM_001290018, NM_019023, NM_001351143, NM_001351144, NR_147056, NR_147057, NR_147058
• Synonyms: FLJ10640; KIAA1933
• Summary: This gene encodes a member of the protein arginine N-methyltransferase family of proteins. The encoded enzyme transfers single methyl groups to arginine residues to generate monomethylarginines on histone proteins as well as other protein substrates. This enzyme plays a role in a wide range of biological processes, including neuronal differentiation, male germ line imprinting, small nuclear ribonucleoprotein biogenesis, and regulation of the Wnt signaling pathway. Mutations in this gene underlie multiple related syndromes in human patients characterized by intellectual disability, short stature and other features. The encoded protein may promote breast cancer cell invasion and metastasis in human patients. [provided by RefSeq, May 2017]