Human MARCH5 activation kit by CRISPRa

CAT#: GA110225

MARCH5 CRISPRa kit - CRISPR gene activation of human membrane associated ring-CH-type finger 5


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol MARCH5
Locus ID 54708
Kit Components

GA110225G1, MARCH5 gRNA vector 1 in pCas-Guide-CRISPRa

GA110225G2, MARCH5 gRNA vector 2 in pCas-Guide-CRISPRa

GA110225G3, MARCH5 gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_017824
Synonyms MARCH-V; MITOL; RNF153
Summary MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2; MIM 608507) and DRP1 (DNM1L; MIM 603850) (Nakamura et al., 2006 [PubMed 16936636]). [supplied by OMIM, Mar 2008]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.