Human CNGB3 activation kit by CRISPRa

CAT#: GA110226

CNGB3 CRISPRa kit - CRISPR gene activation of human cyclic nucleotide gated channel subunit beta 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CNGB3
• Locus ID: 54714
• Kit Components:

  GA110226G1, CNGB3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110226G2, CNGB3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110226G3, CNGB3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_019098
• Synonyms: ACHM1
• Summary: This gene encodes the beta subunit of a cyclic nucleotide-gated ion channel. The encoded beta subunit appears to play a role in modulation of channel function in cone photoreceptors. This heterotetrameric channel is necessary for sensory transduction, and mutations in this gene have been associated with achromatopsia 3, progressive cone dystrophy, and juvenile macular degeneration, also known as Stargardt Disease. [provided by RefSeq, Feb 2010]