Human IL17RD activation kit by CRISPRa

CAT#: GA110244

IL17RD CRISPRa kit - CRISPR gene activation of human interleukin 17 receptor D

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IL17RD
• Locus ID: 54756
• Kit Components:

  GA110244G1, IL17RD gRNA vector 1 in pCas-Guide-CRISPRa

  GA110244G2, IL17RD gRNA vector 2 in pCas-Guide-CRISPRa

  GA110244G3, IL17RD gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001080973, NM_001318864, NM_017563
• Synonyms: HH18; IL-17RD; IL17RLM; SEF
• Summary: This gene encodes a membrane protein belonging to the interleukin-17 receptor (IL-17R) protein family. The encoded protein is a component of the interleukin-17 receptor signaling complex, and the interaction between this protein and IL-17R does not require the interleukin. The gene product also affects fibroblast growth factor signaling, inhibiting or stimulating growth through MAPK/ERK signaling. Alternate splicing generates multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2016]