Human DNAJB12 activation kit by CRISPRa

CAT#: GA110261

DNAJB12 CRISPRa kit - CRISPR gene activation of human DnaJ heat shock protein family (Hsp40) member B12

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DNAJB12
• Locus ID: 54788
• Kit Components:

  GA110261G1, DNAJB12 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110261G2, DNAJB12 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110261G3, DNAJB12 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001002762, NM_017626, NM_001365080, NM_001365081, NR_157570
• Synonyms: DJ10
• Summary: DNAJB12 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain (Ohtsuka and Hata, 2000 [PubMed 11147971]). [supplied by OMIM, Mar 2008]