Human TET2 activation kit by CRISPRa

CAT#: GA110262

TET2 CRISPRa kit - CRISPR gene activation of human tet methylcytosine dioxygenase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TET2
• Locus ID: 54790
• Kit Components:

  GA110262G1, TET2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110262G2, TET2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110262G3, TET2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001127208, NM_017628
• Synonyms: KIAA1546; MDS
• Summary: The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]