Human Dymeclin (DYM) activation kit by CRISPRa

CAT#: GA110275

DYM CRISPRa kit - CRISPR gene activation of human dymeclin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DYM
• Locus ID: 54808
• Kit Components:

  GA110275G1, DYM gRNA vector 1 in pCas-Guide-CRISPRa

  GA110275G2, DYM gRNA vector 2 in pCas-Guide-CRISPRa

  GA110275G3, DYM gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_017653, NM_001353210, NM_001353211, NM_001353212, NM_001353213, NM_001353214, NM_001353215, NM_001353216
• Synonyms: DMC; SMC
• Summary: This gene encodes a protein which regulates Golgi-associated secretory pathways that are essential to endochondral bone formation during early development. This gene is also believed to play a role in early brain development. This gene is widely expressed in embryos and is particularly abundant in chodrocytes and brain tissues. It encodes a peripheral membrane protein which shuttles between the cytosol and Golgi complex. Mutations in this gene are associated with two types of recessive osteochondrodysplasia: Dyggve-Melchior-Clausen (DMC) dysplasia and Smith-McCort (SMC) dysplasia. [provided by RefSeq, Jun 2017]