Human SYTL2 activation kit by CRISPRa

CAT#: GA110304

SYTL2 CRISPRa kit - CRISPR gene activation of human synaptotagmin like 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SYTL2
• Locus ID: 54843
• Kit Components:

  GA110304G1, SYTL2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110304G2, SYTL2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110304G3, SYTL2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001162951, NM_001162952, NM_001162953, NM_001289608, NM_001289609, NM_001289610, NM_032379, NM_032943, NM_206927, NM_206928, NM_206929, NM_206930, NM_001365826, NM_001365828, NM_001365833, NM_001365827, NM_001365829, NM_001365830, NM_001365831, NM_001365832, NM_001365834, NM_001365835
• Synonyms: CHR11SYT; EXO4; PPP1R151; SGA72M; SLP2; SLP2A
• Summary: The protein encoded by this gene is a synaptotagmin-like protein (SLP) that belongs to a C2 domain-containing protein family. The SLP homology domain (SHD) of this protein has been shown to specifically bind the GTP-bound form of Ras-related protein Rab-27A (RAB27A). This protein plays a role in RAB27A-dependent vesicle trafficking and controls melanosome distribution in the cell periphery. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jun 2009]