SYTL2 Human Gene Knockout Kit (CRISPR)

CAT#: KN417584

SYTL2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 linear donor
• Donor DNA: EF1a-GFP-P2A-Puro
• Symbol: SYTL2
• Locus ID: 54843
• Disclaimer: The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001162951, NM_001162952, NM_001162953, NM_001289608, NM_001289609, NM_001289610, NM_032379, NM_032943, NM_206927, NM_206928, NM_206929, NM_206930, NM_001365826, NM_001365828, NM_001365833, NM_001365827, NM_001365829, NM_001365830, NM_001365831, NM_001365832, NM_001365834, NM_001365835
• Synonyms: CHR11SYT; EXO4; PPP1R151; SGA72M; SLP2; SLP2A
• Summary: The protein encoded by this gene is a synaptotagmin-like protein (SLP) that belongs to a C2 domain-containing protein family. The SLP homology domain (SHD) of this protein has been shown to specifically bind the GTP-bound form of Ras-related protein Rab-27A (RAB27A). This protein plays a role in RAB27A-dependent vesicle trafficking and controls melanosome distribution in the cell periphery. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jun 2009]