Human ELP6 activation kit by CRISPRa

CAT#: GA110318

ELP6 CRISPRa kit - CRISPR gene activation of human elongator acetyltransferase complex subunit 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ELP6
• Locus ID: 54859
• Kit Components:

  GA110318G1, ELP6 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110318G2, ELP6 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110318G3, ELP6 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001031703, NM_001031704, NM_017713, NM_001363957
• Synonyms: C3orf75; TMEM103
• Summary: Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Involved in cell migration. [UniProtKB/Swiss-Prot Function]