Human NSUN2 activation kit by CRISPRa

CAT#: GA110345

NSUN2 CRISPRa kit - CRISPR gene activation of human NOP2/Sun RNA methyltransferase 2


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol NSUN2
Locus ID 54888
Kit Components

GA110345G1, NSUN2 gRNA vector 1 in pCas-Guide-CRISPRa

GA110345G2, NSUN2 gRNA vector 2 in pCas-Guide-CRISPRa

GA110345G3, NSUN2 gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001193455, NM_017755, NR_037947
Synonyms MISU; MRT5; SAKI; TRM4
Summary This gene encodes a methyltransferase that catalyzes the methylation of cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. This modification is necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Mar 2011]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.