Human NSD3 (WHSC1L1) activation kit by CRISPRa

CAT#: GA110359

NSD3 CRISPRa kit - CRISPR gene activation of human nuclear receptor binding SET domain protein 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NSD3
• Locus ID: 54904
• Kit Components:

  GA110359G1, NSD3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110359G2, NSD3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110359G3, NSD3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_017778, NM_023034
• Synonyms: NSD3; pp14328
• Summary: This gene is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. This protein methylates histone H3 at lysine residues 4 and 27, which represses gene transcription. Two alternatively spliced variants have been described. [provided by RefSeq, May 2015]