Human ATG16L1 activation kit by CRISPRa

CAT#: GA110481

ATG16L1 CRISPRa kit - CRISPR gene activation of human autophagy related 16 like 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ATG16L1
• Locus ID: 55054
• Kit Components:

  GA110481G1, ATG16L1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110481G2, ATG16L1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110481G3, ATG16L1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001190266, NM_001190267, NM_017974, NM_030803, NM_198890, NM_001363742
• Synonyms: APG16L; ATG16A; ATG16L; IBD10; WDR30
• Summary: The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]