Human WIPI1 activation kit by CRISPRa

CAT#: GA110485

WIPI1 CRISPRa kit - CRISPR gene activation of human WD repeat domain, phosphoinositide interacting 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: WIPI1
• Locus ID: 55062
• Kit Components:

  GA110485G1, WIPI1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110485G2, WIPI1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110485G3, WIPI1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001320772, NM_017983, NR_135470, NR_135471
• Synonyms: ATG18; ATG18A; WIPI49
• Summary: This gene encodes a WD40 repeat protein. Members of the WD40 repeat family are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]