Human Tapasin Related Protein (TAPBPL) activation kit by CRISPRa

CAT#: GA110499

TAPBPL CRISPRa kit - CRISPR gene activation of human TAP binding protein like

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TAPBPL
• Locus ID: 55080
• Kit Components:

  GA110499G1, TAPBPL gRNA vector 1 in pCas-Guide-CRISPRa

  GA110499G2, TAPBPL gRNA vector 2 in pCas-Guide-CRISPRa

  GA110499G3, TAPBPL gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_018009, NM_001351355, NR_147126, NR_147127, NR_147128, NR_147129
• Synonyms: TAPBP-R; TAPBPR
• Summary: Tapasin, or TAPBP (MIM 601962), is a member of the variable-constant Ig superfamily that links major histocompatibility complex (MHC) class I molecules to the transporter associated with antigen processing (TAP; see MIM 170260) in the endoplasmic reticulum (ER). The TAPBP gene is located near the MHC complex on chromosome 6p21.3. TAPBPL is a member of the Ig superfamily that is localized on chromosome 12p13.3, a region somewhat paralogous to the MHC. [supplied by OMIM, Mar 2008]