Human TMLHE activation kit by CRISPRa

CAT#: GA110615

TMLHE CRISPRa kit - CRISPR gene activation of human trimethyllysine hydroxylase, epsilon


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol TMLHE
Locus ID 55217
Kit Components

GA110615G1, TMLHE gRNA vector 1 in pCas-Guide-CRISPRa

GA110615G2, TMLHE gRNA vector 2 in pCas-Guide-CRISPRa

GA110615G3, TMLHE gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001184797, NM_018196
Synonyms AUTSX6; BBOX2; TMLD; TMLH; TMLHED; XAP130
Summary This gene encodes the protein trimethyllysine dioxygenase which is the first enzyme in the carnitine biosynthesis pathway. Carnitine play an essential role in the transport of activated fatty acids across the inner mitochondrial membrane. The encoded protein converts trimethyllysine into hydroxytrimethyllysine. A pseudogene of this gene is found on chromosome X. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.